… a fast fluorometric method able to be used to functionally scrutinize SLC26A4 and its mutants
described in Pendred … Here we show a fast and easy-touse fluorometric method able to …

… iodide [47, 48], most likely acts as a Cl-/I- anion exchanger in … significantly interfere
with pendrin activity. The fluorescence … : Fast fluorometric method for measuring pendrin (SLC26A4) …

… is an iodide transporter [44, 45] most likely acting as a Cl-/I… ) pendrin allelic variants in
which the results of a fluorometric … M: Fast fluorometric method for measuring pendrin (SLC26A4) …

… variants was assessed by measurement of their ion transport activities using a fluorometric
method and determination of the … Fast fluorometric method for measuring pendrin (SLC26A4) …

… interventions aimed at restoring the transport activity of dysfunctional pendrin variants. …
functionally affected and unaffected variants and assessing possible correlations between (a) …

… reported, since TPO activity is supposed to be … transported to the intracellular medium of
cells. These events could explain the rapid and higher effect of iodide increasing SLC26A4 …

… For in vivo fluorometric chloride/iodide measurements, HEK … After expressing pendrin
S523fsX548 , an impaired Cl − /I − … pendrin WT the EYFP fluorescence variations were rapid and …

… Mutations in the SLC26A4 gene encoding for pendrin are … were assessed by fluorometric
methods suitable for measuring … the Cl-/I- and the Cl-/OH- exchange activities of pendrin V239D…

… , ie, measurement of the ion transport activity by a fluorometric … transport activity of pendrin
was determined by measuring … Cl − /HCO 3 − and Cl − /I − exchange activity, localized at the …

… aimed at determining the transport activity of pendrin mutants… : Fast fluorometric method for
measuring pendrin (SLC26A4) … : The Slc26a4 transporter functions as an electroneutral Cl-/I-/…